Libyan Journal of Medical Sciences

CASE REPORT
Year
: 2020  |  Volume : 4  |  Issue : 3  |  Page : 140--142

Disseminated geotrichosis in a patient with prolonged neutropenia: A rare case report and literature review


Arun Prabhakaran Nair1, Sreethish Sasi2, Samar Mahmoud Hashim1, Muna Rahman Al-Maslamani1 
1 Department of Infectious Diseases, Communicable Disease Centre, Hamad Medical Corporation, Doha, Qatar
2 Department of Internal Medicine and Medical Education, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar

Correspondence Address:
Dr. Sreethish Sasi
Department of Internal Medicine and Medical Education, Hamad General Hospital, Al Rayyan Road, P. O. Box: 3050, Doha
Qatar

Disseminated fungemia due to non-Candida yeasts is emerging as an opportunistic infection in hematological malignancies with prolonged neutropenia. Invasive infections by Geotrichum spp. are extremely rare and constitute only about 1% of all non-Candida yeasts. The mortality in such patients is high and is seldom reported in the literature. Here, we describe the case of a middle-aged male with treatment-resistant Hodgkin's lymphoma who developed invasive Geotrichum capitatum infection during his neutropenic phase, with poor response to combination therapy with voriconazole and amphotericin B. He was diagnosed from blood culture but succumbed to death on day 10 of admission in spite of treatment with multiple lines of antifungals. G. capitatum is responsible for fatal fungemia in patients with prolonged neutropenia complicating hematological malignancies. A high index of suspicion is required in this patient group to identify disseminated geotrichosis as delay in treatment worsens mortality.


How to cite this article:
Nair AP, Sasi S, Hashim SM, Al-Maslamani MR. Disseminated geotrichosis in a patient with prolonged neutropenia: A rare case report and literature review.Libyan J Med Sci 2020;4:140-142


How to cite this URL:
Nair AP, Sasi S, Hashim SM, Al-Maslamani MR. Disseminated geotrichosis in a patient with prolonged neutropenia: A rare case report and literature review. Libyan J Med Sci [serial online] 2020 [cited 2022 Nov 28 ];4:140-142
Available from: https://www.ljmsonline.com/article.asp?issn=2588-9044;year=2020;volume=4;issue=3;spage=140;epage=142;aulast=Nair;type=0