• Users Online: 147
  • Print this page
  • Email this page
REVIEW ARTICLE
Year : 2021  |  Volume : 5  |  Issue : 1  |  Page : 2-5

Coeliac disease etiology and pathogenesis


Department of Internal Medicine, Norfolk and Norwich University Hospital, Norwich; MSc Gastroenterology, Queen Marry University of London, London, England

Correspondence Address:
Dr. Ali Khalifa A. Elmdaah
Norfolk and Norwich University Hospital, Coleny Lane, Norwich NR4 7UY
England
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/LJMS.LJMS_87_20

Rights and Permissions

Coeliac disease is a chronic inflammatory autoimmune enteropathy that affects around 1% of people worldwide. It is caused by ingestion of gluten products in people who are genetically predisposed. The pathogenesis involves multifactorial factors of genetic, gluten exposure, and environmental triggers. HLA-DQ2 and HLA-DQ8 are the main responsible genes that contribute to the development of coeliac disease. Both innate and adaptive immune plays role in the pathogenesis. In this article, we will review the causes and pathogenesis of coeliac disease development.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed509    
    Printed0    
    Emailed0    
    PDF Downloaded65    
    Comments [Add]    

Recommend this journal