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ORIGINAL ARTICLE
Year : 2018  |  Volume : 2  |  Issue : 1  |  Page : 26-28

Hormonal profile of some infertile women in bida Nigeria


1 Department of Medical Laboratory Science, Igbinedion University, Edo State, Nigeria
2 Department of Healthcare Services, Standard and Quality Control, Delta State Contributory Health Commission, Asaba, Nigeria
3 Department of Microbiology and Parasitology, College of Medicine, Delta State University, Abraka, Nigeria

Correspondence Address:
Dr. Matthew Eturhobore Adu
Department of Healthcare Services, Standard and Quality control, Delta State Contributory Health Commission, Asaba
Nigeria
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/LJMS.LJMS_36_17

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Background and Aim: The desire for reproduction is a basic human instinct, and it is well known that infertility is one of the psychosocial problems affecting many couples worldwide. The aim of this study is to evaluate the hormonal profile of infertile women in Bida metropolis. Materials and Methods: A total of 200 individuals comprising of 160 infertile and 40 fertile women as controls were recruited into this cross-sectional study in Bida metropolis, Nigeria. Serum luteinizing hormone (LH), follicle stimulating hormone (FSH), prolactin (PRL), progesterone, and estradiol were determined using enzyme immunosorbent assay. Results: Infertile women had significantly higher LH and PRL level (P < 0.05) and statistically lower progesterone and estradiol level (P < 0.05) when compared to fertile women. There was no significant difference in FSH level of infertile women (P > 0.05) when compared to fertile women. Nonmenstruating women (NMW) had lower FSH and progesterone level (P < 0.05) and significantly higher PRL and estradiol level (P < 0.05) when compared to MW. There was no significant difference in LH level of NMW (P > 0.05) when compared to MW. Hormonal abnormalities were observed in 83.3% of the infertile women. This comprises of 30% secondary hypogonadism, 20% hyperprolactinemia/hypogonadism, 13.3% primary hypogonadism, 13.3% hyperestrogenemia, and 6.7% hyperprolactinemia. Conclusion: This study has shown that infertility remains a major problem affecting women of childbearing age. It is therefore recommended that couples should seek medical care on time as well as determine their hormonal status to correct any abnormality that might have arisen.


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